Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949727 | 0.87 | KMT2A (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL29383650 | 0.87 | KMT2A (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL2636596 | 0.87 | KMT2A (0.49) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL6956134 | 0.85 | TDP1 (0.53) | ALDH1A1LMNAMAPTGAAMEN1 | |
| SCHEMBL6956189 | 0.85 | TDP1 (0.53) | ALDH1A1LMNAMAPTGAAMEN1 | |
| SCHEMBL10745473 | 0.84 | ALDH1A1 (0.59) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL10748158 | 0.84 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL10746422 | 0.83 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL744307 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2GAA | |
| SCHEMBL29351076 | 0.81 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022114187-A1 | COMPOUND HAVING INHIBITORY ACTION AGAINST EXCESSIVE MITOCHONDRIAL DIVISIONS | 国立大学法人九州大学 | 2022-06-02 | — | — | WO | disclosed |