SCHEMBL29684206

SCHEMBL29684206

O=C(Nc1cccs1)c1cccc(-c2ccccc2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC8 Q9BY41 1/20 0.57
NR1H4 Q96RI1 1/20 0.51
GRM5 P41594 1/20 0.51
BCHE P06276 1/20 0.51
KCNK3 O14649 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
SERPINE1 P05121 1/20 0.49
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
ALOX15 P16050 1/20 0.49
HTT P42858 1/20 0.49
HSD17B10 Q99714 1/20 0.49
KMO O15229 1/20 0.49
KAT6A Q92794 2/20 0.48
SIRT2 Q8IXJ6 1/20 0.48
GBA1 P04062 1/20 0.48
SUCNR1 Q9BXA5 1/20 0.48
F2R P25116 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3559655 0.85 MEN1 (0.60) KCNK3KCNK9MEN1KMT2AGAA
SCHEMBL29684305 0.78 MGLL (0.71) MEN1KMT2AGAAMAPTALOX15
SCHEMBL2025738 0.77 NR1H4 (0.72) HDAC8NR1H4KCNK3KCNK9MEN1
SCHEMBL18152289 0.76 MEN1 (0.73) HDAC8NR1H4KCNK3KCNK9MEN1
SCHEMBL27760395 0.76 PTPN1 (0.76) HDAC8NR1H4MEN1KMT2ASIRT2
SCHEMBL13601057 0.75 HDAC8 (0.71) HDAC8NR1H4KCNK3KCNK9MEN1
SCHEMBL10363097 0.73 HDAC8 (1.00) HDAC8NR1H4ALOX15HSD17B10KMO
SCHEMBL4683620 0.73 MEN1 (0.59) MEN1KMT2AGAAMAPTALOX15
SCHEMBL8745242 0.73 PTPN1 (0.77) HDAC8NR1H4KCNK3KCNK9KMT2A
SCHEMBL3914463 0.72 NAMPT (0.63) KCNK3MEN1KMT2AGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114763346-B Compounds for inducing cartilage formation and application thereof 华东师范大学 2025-06-10 CN disclosed
CN-114763346-A Compound for inducing chondrogenesis and application thereof 华东师范大学 2022-07-19 CN disclosed