Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307250 | 0.82 | KDM4E (0.42) | ALDH1A1LPLLIPGHTTKDM4E | |
| SCHEMBL21645897 | 0.81 | PDGFRB (0.59) | PDGFRBPDGFRAALDH1A1NPC1POLB | |
| SCHEMBL15191712 | 0.80 | LPL (0.49) | LPLLIPGCYP1A2EGFR | |
| SCHEMBL16431930 | 0.78 | PDGFRB (0.59) | PDGFRBPDGFRAALDH1A1NPC1POLB | |
| SCHEMBL21541550 | 0.77 | ALDH1A1 (0.39) | PDGFRBPDGFRAALDH1A1NPC1POLB | |
| SCHEMBL22323962 | 0.77 | PDGFRB (0.47) | PDGFRBPDGFRAALDH1A1NPC1POLB | |
| SCHEMBL29447097 | 0.77 | PDGFRB (0.47) | PDGFRBPDGFRAALDH1A1NPC1POLB | |
| SCHEMBL31149524 | 0.75 | EGFR (0.36) | LPLLIPGEGFR | |
| SCHEMBL31513479 | 0.75 | ALDH1A1 (0.49) | PDGFRBPDGFRAALDH1A1NPC1POLB | |
| SCHEMBL418496 | 0.75 | ALDH1A1 (0.49) | PDGFRBPDGFRAALDH1A1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |