SCHEMBL29684472

SCHEMBL29684472

COCCOc1cc(Cl)ccc1N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 2/20 0.49
HTR2B P41595 1/20 0.49
PLAU P00749 1/20 0.47
S1PR4 O95977 4/20 0.43
MAPK1 P28482 2/20 0.42
HTT P42858 2/20 0.42
LMNA P02545 1/20 0.42
ALDH1A1 P00352 3/20 0.42
CYP3A4 P08684 3/20 0.42
TSHR P16473 2/20 0.42
ALOX15 P16050 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPT P10636 3/20 0.42
POLB P06746 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15716191 1.00 HTR2C (0.49) HTR2CHTR2BPLAUS1PR4MAPK1
SCHEMBL8263900 0.91 LMNA (0.48) HTR2CHTR2BPLAUS1PR4MAPK1
SCHEMBL29684402 0.86 HTR2C (0.52) HTR2CHTR2BPLAUS1PR4MAPK1
SCHEMBL360551 0.86 HTR2C (0.52) HTR2CHTR2BPLAUS1PR4MAPK1
SCHEMBL3784669 0.84 MAPT (0.51) HTR2CHTR2BS1PR4MAPK1HTT
SCHEMBL14345658 0.83 HTR2C (0.52) HTR2CHTR2BPLAUS1PR4MAPK1
SCHEMBL3785269 0.82 CYP1A2 (0.58) HTR2CMAPK1HTTALDH1A1CYP3A4
SCHEMBL11228216 0.81 ALDH1A1 (0.49) HTR2CHTR2BPLAUMAPK1HTT
SCHEMBL29835019 0.81 ALDH1A1 (0.49) HTR2CHTR2BPLAUMAPK1HTT
SCHEMBL9073879 0.81 ALDH1A1 (0.63) MAPK1HTTALDH1A1CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114763346-B Compounds for inducing cartilage formation and application thereof 华东师范大学 2025-06-10 CN disclosed
CN-114763346-A Compound for inducing chondrogenesis and application thereof 华东师范大学 2022-07-19 CN disclosed