Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.38 |
| ▸ | FEN1 | P39748 | 4/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619269 | 0.83 | CCR1 (0.34) | ADORA2ACCR1RAB9ACCR5KDR | |
| SCHEMBL29727041 | 0.79 | ADORA2A (0.46) | RPS6KA3ALOX5APFEN1CDC7ADORA1 | |
| SCHEMBL24619110 | 0.79 | ADORA2A (0.46) | RPS6KA3ALOX5APFEN1CDC7ADORA1 | |
| SCHEMBL29727074 | 0.76 | P2RX3 (0.39) | RPS6KA3ALOX5APFEN1CDC7ADORA1 | |
| SCHEMBL30309518 | 0.74 | RPS6KA3 (0.37) | RPS6KA3CDC7ADORA2A | |
| SCHEMBL24207564 | 0.72 | KDM4E (0.48) | CCR1RAB9ACCR5 | |
| SCHEMBL30309561 | 0.71 | RPS6KA3 (0.35) | RPS6KA3CDC7ADORA1ADORA2AKDR | |
| SCHEMBL29402856 | 0.70 | CDK4 (0.55) | KDR | |
| SCHEMBL30818384 | 0.70 | CDK4 (0.55) | KDR | |
| SCHEMBL16892106 | 0.70 | CDK4 (0.55) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022113003-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-06-02 | — | — | WO | disclosed |