Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 3/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29727041 | 1.00 | ADORA2A (0.46) | ADORA2AADORA1ADORA3CDC7RPS6KA3 | |
| SCHEMBL24619115 | 0.83 | ADORA2A (0.41) | ADORA2AADORA1ADORA3KDM4ENPC1 | |
| SCHEMBL29684604 | 0.79 | RPS6KA3 (0.43) | ADORA2AADORA1ADORA3CDC7RPS6KA3 | |
| SCHEMBL29669589 | 0.79 | ADORA2A (0.57) | ADORA2AADORA1ADORA3 | |
| SCHEMBL20392592 | 0.79 | ADORA2A (0.57) | ADORA2AADORA1ADORA3 | |
| SCHEMBL20392690 | 0.78 | ADORA2A (0.56) | ADORA2AADORA1ADORA3 | |
| SCHEMBL20392552 | 0.77 | ADORA2A (0.56) | ADORA2AADORA1ADORA3NPC1 | |
| SCHEMBL20600822 | 0.76 | FEN1 (0.45) | ADORA2AADORA1ADORA3FEN1ALOX5AP | |
| SCHEMBL20667486 | 0.76 | ADORA2A (0.54) | ADORA2AADORA1ADORA3FEN1ALOX5AP | |
| SCHEMBL20392609 | 0.76 | ADORA2A (0.60) | ADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |