Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24498537 | 1.00 | LGMN (0.52) | LGMNMAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL20073418 | 0.87 | LMNA (0.44) | LGMNMAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL26121387 | 0.86 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL24498526 | 0.85 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1GAALMNA | |
| SCHEMBL26513075 | 0.84 | MAPT (0.42) | LGMNMAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL24497560 | 0.84 | MAPT (0.43) | LGMNMAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL24498232 | 0.82 | MAPT (0.40) | LGMNMAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL27181513 | 0.80 | MAPT (0.63) | MAPTSMN1; SMN2ALDH1A1LMNAPKM | |
| SCHEMBL2060694 | 0.77 | LGMN (0.54) | LGMNMAPTSMN1; SMN2ALDH1A1GAA | |
| SCHEMBL20073397 | 0.76 | TYK2 (0.48) | TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-114901656-B | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114901656-A | Hydroximic acid ester compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2022-08-12 | — | — | CN | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |