Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | BCR | P11274 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447043 | 0.84 | NNMT (0.55) | NNMTGRM5KDM4E | |
| SCHEMBL2516351 | 0.84 | NNMT (0.55) | NNMTGRM5KDM4E | |
| Hydrochloric Acid SCHEMBL30478323 | 0.82 | NNMT (0.53) | NNMTGRM5KDM4E | |
| Hydrochloric Acid SCHEMBL31575506 | 0.82 | NNMT (0.53) | NNMTGRM5KDM4E | |
| Hydrochloric Acid SCHEMBL3494122 | 0.82 | NNMT (0.53) | NNMTGRM5KDM4E | |
| SCHEMBL29039314 | 0.77 | PTGS1 (0.59) | NNMTCDK5CDK5R1POLB | |
| SCHEMBL30490221 | 0.77 | PTGS1 (0.59) | NNMTCDK5CDK5R1POLB | |
| SCHEMBL180474 | 0.76 | ABL1 (0.48) | ABL1BCRKDM4EALDH1A1 | |
| SCHEMBL26107386 | 0.76 | ABL1 (0.48) | ABL1BCRKDM4E | |
| SCHEMBL14607583 | 0.75 | HCAR3 (0.76) | NNMTHCAR3GRM5JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |
| WO-2022117016-A1 | HYDROXAMATE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 深圳微芯生物科技股份有限公司 | 2022-06-09 | — | — | WO | disclosed |