Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CASR | P41180 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29687123 | 0.87 | FPR2 (0.81) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL29686977 | 0.84 | CA12 (0.56) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL20335073 | 0.84 | MEN1 (0.61) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL11579877 | 0.84 | USP2 (0.61) | FPR2USP2RAB9AKMT2ACRHBP | |
| SCHEMBL29686493 | 0.84 | FPR2 (0.63) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL20611567 | 0.84 | FPR2 (0.63) | FPR2CA12CA1CA2CA9 | |
| SCHEMBL5842757 | 0.80 | CTSL (0.67) | FPR2LMNAALDH1A1ALOX15 | |
| SCHEMBL5842766 | 0.80 | CTSL (0.67) | FPR2LMNAALDH1A1ALOX15 | |
| SCHEMBL20241469 | 0.80 | TAAR1 (0.54) | ALDH1A1POLBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL14026537 | 0.80 | MEN1 (0.53) | RAB9AALDH1A1KMT2ATHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265083-B1 | SUBSTITUTED UREA DEPSIPEPTIDE ANALOGS AS ACTIVATORS OF THE CLPP ENDOPEPTIDASE | ST JUDE CHILDRENS RES HOSPITAL (US) | 2022-07-06 | — | — | EP | disclosed |