Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 6/20 | 0.54 |
| ▸ | MMP8 | P22894 | 5/20 | 0.54 |
| ▸ | MMP17 | Q9ULZ9 | 4/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20134812 | 1.00 | MMP14 (0.54) | MMP14MMP8MMP17MMP2MMP1 | |
| SCHEMBL20134755 | 0.90 | MMP14 (0.53) | MMP14MMP8MMP17MMP2MMP1 | |
| SCHEMBL20134964 | 0.85 | MMP14 (0.51) | MMP14MMP8MMP17MMP2MMP1 | |
| SCHEMBL20135060 | 0.81 | MMP14 (0.45) | MMP14MMP8MMP17MMP2MMP1 | |
| SCHEMBL20135269 | 0.79 | MMP14 (0.43) | MMP14MMP8MMP17MMP2MMP1 | |
| SCHEMBL29688624 | 0.79 | MMP14 (0.43) | MMP14MMP8MMP17MMP2MMP1 | |
| SCHEMBL542441 | 0.79 | MMP14 (0.46) | MMP14MMP8MMP17MMP2MMP1 | |
| SCHEMBL3410690 | 0.78 | ADAM17 (0.60) | MMP14MMP8MMP17MMP2MMP1 | |
| SCHEMBL20135652 | 0.78 | ADAM17 (0.60) | MMP14MMP8MMP17MMP2MMP1 | |
| SCHEMBL20135513 | 0.78 | ADAM17 (0.60) | MMP14MMP8MMP17MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |