Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135091 | 1.00 | HTR2A (0.46) | HTR2AHTR7HTR1AHTR1FHTT | |
| SCHEMBL20135089 | 1.00 | HTR2A (0.46) | HTR2AHTR7HTR1AHTR1FHTT | |
| SCHEMBL20135010 | 0.94 | JAK1 (0.48) | HTR2AHTR7 | |
| SCHEMBL20135007 | 0.94 | JAK1 (0.48) | HTR2AHTR7 | |
| SCHEMBL20135284 | 0.90 | HTR2A (0.39) | HTR2AHTR7HTR1AHTR1FDRD3 | |
| SCHEMBL29688529 | 0.90 | HTR2A (0.39) | HTR2AHTR7HTR1AHTR1FDRD3 | |
| SCHEMBL20135282 | 0.90 | HTR2A (0.39) | HTR2AHTR7HTR1AHTR1FDRD3 | |
| SCHEMBL20134967 | 0.89 | MAPK7 (0.44) | HTR2AHTR1ALMNA | |
| SCHEMBL20134965 | 0.89 | MAPK7 (0.44) | HTR2AHTR1ALMNA | |
| SCHEMBL20135346 | 0.83 | RBP4 (0.42) | HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |