Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29688529 | 1.00 | HTR2A (0.39) | HTR2AHTR7DRD3HTR1AHTR1F | |
| SCHEMBL20135282 | 1.00 | HTR2A (0.39) | HTR2AHTR7DRD3HTR1AHTR1F | |
| SCHEMBL20135091 | 0.90 | HTR2A (0.46) | HTR2AHTR7DRD3HTR1AHTR1F | |
| SCHEMBL20135089 | 0.90 | HTR2A (0.46) | HTR2AHTR7DRD3HTR1AHTR1F | |
| SCHEMBL29688909 | 0.90 | HTR2A (0.46) | HTR2AHTR7DRD3HTR1AHTR1F | |
| SCHEMBL20134967 | 0.89 | MAPK7 (0.44) | HTR2AHTR1AADAM17 | |
| SCHEMBL20134965 | 0.89 | MAPK7 (0.44) | HTR2AHTR1AADAM17 | |
| SCHEMBL20135007 | 0.85 | JAK1 (0.48) | HTR2AHTR7 | |
| SCHEMBL20135010 | 0.85 | JAK1 (0.48) | HTR2AHTR7 | |
| SCHEMBL20135335 | 0.85 | ADAMTS5 (0.41) | HTR2ADRD3ADAMTS5ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-09-10 | — | — | US | disclosed |
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2019-03-14 | — | — | US | disclosed |
| EP-3321256-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2018-05-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190077787-A1 | NOVEL IMIDE DERIVATIVES AND USE THEREOF AS MEDICINE | MMP9, MMP10, MMP1 | HTR2A 3616/4885HTR7 3585/4885DRD3 3587/4885 |
| US-10407408-B2 | Imide derivatives and use thereof as medicine | MMP9, MMP2, MMP1 | HTR2A 3803/4885HTR7 3611/4885DRD3 3757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.