Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 10/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135023 | 1.00 | ADAMTS5 (0.38) | ADAMTS5ADAM17MMP2ADAMTS4MMP1 | |
| SCHEMBL29688718 | 0.96 | ADAMTS5 (0.39) | ADAMTS5ADAM17MMP2ADAMTS4MMP1 | |
| SCHEMBL20135609 | 0.96 | ADAMTS5 (0.39) | ADAMTS5ADAM17MMP2ADAMTS4MMP1 | |
| SCHEMBL20134997 | 0.94 | ADAMTS5 (0.38) | ADAMTS5ADAM17ALDH1A1MEN1KMT2A | |
| SCHEMBL29688890 | 0.87 | HTT (0.40) | ADAMTS5ADAM17MMP2ADAMTS4MMP1 | |
| SCHEMBL20135271 | 0.87 | HTT (0.40) | ADAMTS5ADAM17MMP2ADAMTS4MMP1 | |
| SCHEMBL29688749 | 0.86 | ADAMTS5 (0.40) | ADAMTS5ADAM17MMP2ADAMTS4MMP1 | |
| SCHEMBL20135181 | 0.86 | ADAMTS5 (0.40) | ADAMTS5ADAM17MMP2ADAMTS4MMP1 | |
| SCHEMBL20134799 | 0.85 | ALDH1A1 (0.39) | ADAMTS5ADAM17MMP2ALDH1A1CRBN | |
| SCHEMBL20134796 | 0.85 | ALDH1A1 (0.39) | ADAMTS5ADAM17MMP2ALDH1A1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |