Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 17/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 9/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135694 | 1.00 | ADAMTS5 (0.42) | ADAMTS5ADAM17MMP2MMP1MMP13 | |
| SCHEMBL20135062 | 0.95 | ADAMTS5 (0.43) | ADAMTS5ADAM17MMP2MMP1MMP13 | |
| SCHEMBL20134893 | 0.95 | ADAMTS5 (0.43) | ADAMTS5ADAM17MMP2MMP1MMP13 | |
| SCHEMBL20135444 | 0.95 | ADAMTS5 (0.43) | ADAMTS5ADAM17MMP2MMP1MMP13 | |
| SCHEMBL20135581 | 0.92 | ADAMTS5 (0.40) | ADAMTS5ADAM17MMP2MMP1MMP13 | |
| SCHEMBL29688879 | 0.92 | ADAMTS5 (0.40) | ADAMTS5ADAM17MMP2MMP1MMP13 | |
| SCHEMBL20135625 | 0.92 | ADAM17 (0.41) | ADAMTS5ADAM17MMP2MMP1MMP13 | |
| SCHEMBL29688941 | 0.92 | ADAM17 (0.41) | ADAMTS5ADAM17MMP2MMP1MMP13 | |
| SCHEMBL20134951 | 0.92 | ADAM17 (0.41) | ADAMTS5ADAM17MMP2MMP1MMP13 | |
| SCHEMBL20134947 | 0.92 | ADAM17 (0.41) | ADAMTS5ADAM17MMP2MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |