Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20135127 | 1.00 | LMNA (0.44) | LMNASMN1; SMN2MAPTGAAATM | |
| SCHEMBL29689268 | 1.00 | LMNA (0.44) | LMNASMN1; SMN2MAPTGAAATM | |
| SCHEMBL20135123 | 1.00 | LMNA (0.44) | LMNASMN1; SMN2MAPTGAAATM | |
| SCHEMBL29688842 | 1.00 | LMNA (0.44) | LMNASMN1; SMN2MAPTGAAATM | |
| SCHEMBL20135401 | 1.00 | LMNA (0.44) | LMNASMN1; SMN2MAPTGAAATM | |
| SCHEMBL20135371 | 0.93 | LMNA (0.43) | LMNASMN1; SMN2MAPTGAAATM | |
| SCHEMBL29688412 | 0.93 | LMNA (0.43) | LMNASMN1; SMN2MAPTGAAATM | |
| SCHEMBL29688752 | 0.92 | NPSR1 (0.41) | LMNASMN1; SMN2MAPTTSHRKMT2A | |
| SCHEMBL20135245 | 0.92 | NPSR1 (0.41) | LMNASMN1; SMN2MAPTTSHRKMT2A | |
| SCHEMBL20134750 | 0.91 | ALDH1A1 (0.37) | LMNASMN1; SMN2MAPTHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |