Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16035588 | 1.00 | P2RX7 (0.80) | P2RX7CYP2C19 | |
| SCHEMBL16035591 | 1.00 | P2RX7 (0.80) | P2RX7CYP2C19 | |
| SCHEMBL16037327 | 0.89 | P2RX7 (1.00) | P2RX7CYP2C19 | |
| SCHEMBL29689310 | 0.89 | P2RX7 (1.00) | P2RX7CYP2C19 | |
| SCHEMBL16037329 | 0.89 | P2RX7 (1.00) | P2RX7CYP2C19 | |
| SCHEMBL16035791 | 0.84 | P2RX7 (1.00) | P2RX7CYP2C19 | |
| SCHEMBL16035789 | 0.84 | P2RX7 (1.00) | P2RX7CYP2C19 | |
| SCHEMBL18860792 | 0.80 | P2RX7 (0.67) | P2RX7CYP2C19 | |
| Zanvipixant SCHEMBL16035842 | 0.79 | P2RX7 (1.00) | P2RX7CYP2C19 | |
| Zanvipixant SCHEMBL31347780 | 0.79 | P2RX7 (1.00) | P2RX7CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820770-B2 | P2X7 modulators | JANSSEN PHARMACEUTICA NV (BE) | 2023-11-21 | — | — | US | disclosed |
| US-20220213095-A1 | P2X7 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820770-B2 | P2X7 modulators | P2RX2, P2RX7, P2RY2 | P2RX7 2/4885CYP2C19 704/4885 |
| US-20220213095-A1 | P2X7 MODULATORS | P2RX2, P2RX7, P2RY2 | P2RX7 2/4885CYP2C19 704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.