SCHEMBL4464142

SCHEMBL4464142

COc1cc(CCc2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.75
HTR2C P28335 1/20 0.75
HTR2B P41595 1/20 0.75
TUBB4A P04350 3/20 0.73
TUBB P07437 3/20 0.73
TUBA3C P0DPH7 3/20 0.73
TUBA1B P68363 3/20 0.73
TUBA4A P68366 3/20 0.73
TUBB4B P68371 3/20 0.73
TUBB3 Q13509 3/20 0.73
TUBB2A Q13885 3/20 0.73
TUBB8 Q3ZCM7 3/20 0.73
TUBA3E Q6PEY2 3/20 0.73
TUBA1A Q71U36 3/20 0.73
TUBA1C Q9BQE3 3/20 0.73
TUBB6 Q9BUF5 3/20 0.73
TUBB2B Q9BVA1 3/20 0.73
TUBB1 Q9H4B7 3/20 0.73
CYP19A1 P11511 1/20 0.70
PTGS2 P35354 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7424861 0.90 HTR2A (0.69) HTR2AHTR2CHTR2BTUBB4ATUBB
SCHEMBL8864538 0.89 HTR2A (0.62) HTR2AHTR2CHTR2BTUBB4ATUBB
SCHEMBL2500546 0.88 PTGS2 (0.68) HTR2AHTR2CHTR2BTUBB4ATUBB
SCHEMBL29286367 0.87 TUBB4A (0.74) HTR2AHTR2CHTR2BTUBB4ATUBB
SCHEMBL20696534 0.87 TUBB4A (0.74) HTR2AHTR2CHTR2BTUBB4ATUBB
SCHEMBL21530612 0.87 TUBB4A (0.70) HTR2AHTR2CHTR2BTUBB4ATUBB
SCHEMBL30079962 0.87 TUBB4A (0.74) HTR2AHTR2CHTR2BTUBB4ATUBB
SCHEMBL29689431 0.87 TUBB4A (0.74) HTR2AHTR2CHTR2BTUBB4ATUBB
Mescaline SCHEMBL25170531 0.86 HTR2A (1.00) HTR2AHTR2CHTR2BTUBB4ATUBB
SCHEMBL3127096 0.86 HTR2A (0.64) HTR2AHTR2CHTR2BTUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022236790-A1 APPLICATION OF EXTRACT OF DENDROBIUM CAPILLIPES RCHB.F., DENDROBIUM LINDLEYI STENDEL AND DENDROBIUM SECUNDUM(BLUME)LINDL. AS α-GLUCOSIDASE INHIBITOR 中国热带农业科学院热带生物技术研究所 2022-11-17 WO claimed
CN-118771956-A Carboxylic acid decarboxylation coupling conversion method using sulfur hexafluoride as oxidizing reagent 国网安徽省电力有限公司电力科学研究院 2024-10-15 CN disclosed
WO-2022236790-A1 APPLICATION OF EXTRACT OF DENDROBIUM CAPILLIPES RCHB.F., DENDROBIUM LINDLEYI STENDEL AND DENDROBIUM SECUNDUM(BLUME)LINDL. AS α-GLUCOSIDASE INHIBITOR 中国热带农业科学院热带生物技术研究所 2022-11-17 WO disclosed
US-7528271-B2 Intermediates, process for their preparation and synthesis of 1,4-benzoquiones BERGEN TEKNOLOGIOVERFORING AS (NO) 2009-05-05 US disclosed
WO-2008140328-A2 NOVEL INTERMEDIATES, PROCESS FOR THEIR PREPARATION AND SYNTHESIS OF 1,4-BENZOQUINONES BERGEN TEKNOLOGIOVERFORING AS (NO) 2008-11-20 WO disclosed
US-20080287702-A1 Novel intermediates, process for their preparation and synthesis of 1, 4-benzoquiones BERGEN TEKNOLOGIOVERFORING AS (NO) 2008-11-20 US disclosed
EP-0154887-B1 NEW 2,5-DIARYL TETRAHYDROTHIOPHENES AND ANALOGS THEREOF AS PAF-ANTAGONISTS MERCK & CO. INC. (US) 1989-01-25 EP disclosed
EP-0199324-A2 New 2,5-diaryl tetryhydrofurans and analogs thereof as paf antagonists MERCK & CO. INC. (US) 1986-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080287702-A1 Novel intermediates, process for their preparation and synthesis of 1, 4-benzoquiones SQOR, NDUFB10, UQCRB HTR2A 1559/4885HTR2C 1778/4885HTR2B 1065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.