Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.47 |
| ▸ | REN | P00797 | 4/20 | 0.43 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | FAP | Q12884 | 2/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PEPD | P12955 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30353946 | 0.91 | ACE (0.41) | ACERENFAPACE2 | |
| SCHEMBL31634209 | 0.89 | ACE (0.41) | ACERENDPP4FAPPREP | |
| SCHEMBL29947689 | 0.88 | ACE (0.46) | ACERENDPP4FAPPREP | |
| SCHEMBL29589425 | 0.85 | ACE (0.43) | ACERENDPP4FAPPREP | |
| SCHEMBL29464996 | 0.85 | ACE (0.48) | ACERENDPP4FAPPREP | |
| SCHEMBL30705446 | 0.84 | ACE (0.44) | ACERENDPP4FAPPREP | |
| SCHEMBL10396256 | 0.84 | MEN1 (0.49) | ACEDPP4FAPMAPTDPP8 | |
| SCHEMBL31070023 | 0.84 | OPRM1 (0.41) | DPP4FAPPREP | |
| SCHEMBL30605149 | 0.84 | ACE (0.50) | ACERENDPP4FAPPREP | |
| SCHEMBL29670885 | 0.84 | ACE (0.50) | ACERENDPP4FAPPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3443096-B1 | COMPOSITIONS AND METHODS FOR SELECTIVE EXPRESSION OF CHIMERIC ANTIGEN RECEPTORS | NOVARTIS AG (CH) | 2023-03-01 | — | — | EP | claimed |
| CN-117384991-A | Preparation method and application of high-bioactivity cyclic peptide | 上海中翊日化有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117017844-A | Filamentous yeast-like fungus fermentation product composition with multiple effects and application thereof | 上海中翊日化有限公司 | 2023-11-10 | — | — | CN | disclosed |
| CN-114574536-A | Collagen tripeptide and enzymatic preparation method thereof | 华南理工大学 | 2022-06-03 | — | — | CN | disclosed |