Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30558183 | 0.88 | MEN1 (0.44) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL29409428 | 0.87 | OPRK1 (0.49) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL30490560 | 0.87 | CALCRL (0.43) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL29589425 | 0.86 | ACE (0.43) | DPP4FAPACE | |
| SCHEMBL30558185 | 0.86 | MEN1 (0.44) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL30558196 | 0.86 | MEN1 (0.44) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL11368293 | 0.85 | ACE (0.43) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL11368299 | 0.85 | ACE (0.43) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL29689560 | 0.84 | ACE (0.47) | MAPTDPP4DPP8DPP9DPP7 | |
| SCHEMBL29727257 | 0.84 | ACE (0.41) | DPP4FAPACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921941-A | TRIPEPTIDE ESTERS | SCHERING CORPORATION (US) | 1990-05-01 | — | — | US | claimed |
| WO-1989000165-A1 | ORALLY ACTIVE ANTIANDROGENS | SCHERING CORPORATION (US) | 1989-01-12 | — | — | WO | claimed |
| US-4921941-A | TRIPEPTIDE ESTERS | SCHERING CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| WO-1989000165-A1 | ORALLY ACTIVE ANTIANDROGENS | SCHERING CORPORATION (US) | 1989-01-12 | — | — | WO | disclosed |