Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.42 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29218244 | 0.87 | KDM5B (0.42) | KDM5BMCL1IRAK4FGFR1FLT3 | |
| SCHEMBL19277419 | 0.87 | CYP4F2 (0.43) | KDM5BMCL1IRAK4FGFR1FLT3 | |
| SCHEMBL26130683 | 0.87 | KDM5B (0.42) | KDM5BMCL1IRAK4FGFR1FLT3 | |
| SCHEMBL30895651 | 0.87 | KDM5B (0.42) | KDM5BMCL1IRAK4FGFR1FLT3 | |
| SCHEMBL26131431 | 0.87 | KDM5B (0.44) | KDM5BMCL1IRAK4FGFR1FLT3 | |
| SCHEMBL29937943 | 0.86 | KDM5B (0.43) | KDM5BMCL1FGFR1FLT3FGFR2 | |
| SCHEMBL31434739 | 0.84 | FLT3 (0.45) | KDM5BMCL1FGFR1FLT3FGFR2 | |
| SCHEMBL31434638 | 0.84 | KDM5B (0.43) | KDM5BMCL1FGFR1FLT3FGFR2 | |
| SCHEMBL28375403 | 0.83 | MCL1 (0.45) | KDM5BMCL1FGFR1FLT3FGFR2 | |
| SCHEMBL28545279 | 0.83 | MCL1 (0.46) | KDM5BMCL1FGFR1FLT3FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112608492-B | Metal organic framework material of cobalt chain based on double-end pyrazole ligand, preparation and benzene adsorption application | 北京工业大学 | 2022-05-27 | — | — | CN | disclosed |