Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.45 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 5/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31434638 | 0.88 | KDM5B (0.43) | FLT3FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL19277419 | 0.84 | CYP4F2 (0.43) | FLT3FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL29689591 | 0.84 | KDM5B (0.44) | FLT3FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL22075273 | 0.84 | FGFR3 (0.56) | FLT3FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL29218244 | 0.82 | KDM5B (0.42) | FLT3FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL26130683 | 0.82 | KDM5B (0.42) | FLT3FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL30895651 | 0.82 | KDM5B (0.42) | FLT3FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL28375403 | 0.81 | MCL1 (0.45) | FLT3FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL878011 | 0.80 | KDM5B (0.38) | FLT3FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL20590902 | 0.78 | CYP4F2 (0.54) | FLT3FGFR1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025085347-A1 | IL4I1 INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME LLC (US) | 2025-04-24 | — | — | WO | disclosed |