Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | XDH | P47989 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1458953 | 1.00 | TDP1 (0.52) | TDP1CA1CA2CA12CA7 | |
| SCHEMBL18062669 | 0.92 | RAB9A (0.46) | TDP1CA1CA2CA12CA7 | |
| SCHEMBL12767850 | 0.86 | CA1 (0.46) | TDP1CA1CA2CA12CA7 | |
| SCHEMBL2417938 | 0.85 | TDP1 (0.52) | TDP1CA1CA2CA12CA7 | |
| SCHEMBL29587663 | 0.85 | TDP1 (0.52) | TDP1CA1CA2CA12CA7 | |
| SCHEMBL14829748 | 0.81 | KDM4E (0.56) | TDP1CA1CA2CA12CA7 | |
| SCHEMBL18713916 | 0.81 | CA1 (0.67) | TDP1CA1CA2CA12CA7 | |
| SCHEMBL35783 | 0.80 | MAPT (0.63) | TDP1CA1CA2CA12CA7 | |
| SCHEMBL30029511 | 0.80 | MAPT (0.63) | TDP1CA1CA2CA12CA7 | |
| SCHEMBL629923 | 0.80 | KDM4E (0.64) | TDP1CA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727591-A1 | SMARCA2 DEGRADERS AND USES THEREOF | Astrazeneca AB (SE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256988-A1 | SMARCA2 DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2024-12-19 | — | — | WO | disclosed |
| CN-112689637-B | Imidazopyridone compounds | 橘生药品工业株式会社 | 2023-11-10 | — | — | CN | disclosed |
| CN-114675458-A | High-performance hydrogen bond organic framework material electrochromic device | 辽宁大学 | 2022-06-28 | — | — | CN | disclosed |