SCHEMBL35783

SCHEMBL35783

COC(=O)c1ccc(C)c(C)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.63
GAA P10253 2/20 0.63
LMNA P02545 2/20 0.63
TDP1 Q9NUW8 1/20 0.59
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
CA12 O43570 2/20 0.59
CA7 P43166 2/20 0.59
CA9 Q16790 2/20 0.59
CA14 Q9ULX7 2/20 0.59
XDH P47989 1/20 0.59
ALDH1A1 P00352 5/20 0.56
NOTUM Q6P988 1/20 0.54
HPGD P15428 3/20 0.53
KDM4E B2RXH2 2/20 0.53
HSD17B10 Q99714 2/20 0.53
GLA P06280 1/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
ATM Q13315 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30029511 1.00 MAPT (0.63) MAPTGAALMNATDP1CA1
SCHEMBL16937873 0.85 TDP1 (0.57) MAPTGAALMNATDP1CA1
SCHEMBL45823 0.85 KDM4E (0.67) MAPTGAALMNATDP1CA1
SCHEMBL6113434 0.84 CES2 (0.53) MAPTGAALMNATDP1ALDH1A1
SCHEMBL13830583 0.84 TDP1 (0.57) MAPTGAALMNATDP1CA1
4-Methylbenzoic Acid Methyl Ester SCHEMBL30797091 0.84 TDP1 (0.67) MAPTGAALMNATDP1CA1
SCHEMBL30809635 0.83 CA1 (0.71) MAPTGAALMNATDP1CA1
SCHEMBL821898 0.83 KDM4E (0.59) MAPTGAALMNATDP1CA1
SCHEMBL197972 0.83 CA1 (0.71) MAPTGAALMNATDP1CA1
SCHEMBL172476 0.83 CA1 (0.71) MAPTGAALMNATDP1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 323 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4076924-A CATALYST COMPRISING A TITANIUM COMPONENT AND A GROUP I TO III ORGANO-METAL COMPOUND MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1978-02-28 US claimed
EP-4536363-A1 SULFAMIDE DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS Nikang Therapeutics, Inc. (US) 2025-04-16 EP disclosed
US-20240408216-A1 PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE JING MEDICINE TECHNOLOGY (SHANGHAI) LTD. (CN) 2024-12-12 US disclosed
US-12097629-B2 Razor cartridge BIC Violex Single Member S.A. (GR) 2024-09-24 US disclosed
EP-4361163-A1 PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE JING MEDICINE TECHNOLOGY (SHANGHAI) LTD. (CN) 2024-05-01 EP disclosed
US-11919183-B2 Razor cartridge BIC Violex Single Member S.A. (GR) 2024-03-05 US disclosed
EP-3869268-B1 MATERIAL FOR FORMING ORGANIC FILM, PATTERNING PROCESS, AND POLYMER SHINETSU CHEMICAL CO (JP) 2024-01-17 EP disclosed
US-20240009874-A1 RAZOR CARTRIDGE BIC Violex Single Member S.A. (GR) 2024-01-11 US disclosed
WO-2023240024-A1 SULFAMIDE DERIVATIVES AS CYCLIN-DEPENDENT KINASE 2 INHIBITORS NIKANG THERAPEUTICS, INC. (US) 2023-12-14 WO disclosed
CN-117203216-A Protein inhibitor or degradation agent, pharmaceutical composition containing same and medical application 和径医药科技(上海)有限公司 2023-12-08 CN disclosed
EP-0464959-A2 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1992-01-08 EP disclosed
US-5026856-A Bactericides WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1991-06-25 US disclosed
US-5015777-A Reaction of an acetophenone and an aliphatic ester or an ester of benzoic acid in the presence of sodium alkoxide condensation agent in an aromatic solvent WITCO CORPORATION (US) 1991-05-14 US disclosed
EP-0343560-A2 Isoindoline derivative WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) 1989-11-29 EP disclosed
CN-1037163-A Carbon black filled foams CELOTEX CORP (US) 1989-11-15 CN disclosed
EP-0182872-B1 A PROCESS FOR THE PREPARATION OF CYCLOBUTENE-SUBSTITUTED AROMATIC HYDROCARBONS THE DOW CHEMICAL COMPANY (US) 1989-11-08 EP disclosed
US-4833264-A INTERMEDIATES FOR NAPHTHALOCYANINE DYES HITACHI CHEMICAL CO., LTD. (JP) 1989-05-23 US disclosed
EP-0284369-A2 5- or 6-alkoxycarbonyl-2,3-dicyanonaphthalenes and process for production thereof Hitachi Chemical Co., Ltd. (JP) 1988-09-28 EP disclosed
EP-0284370-A2 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1988-09-28 EP disclosed
US-4076924-A CATALYST COMPRISING A TITANIUM COMPONENT AND A GROUP I TO III ORGANO-METAL COMPOUND MITSUI PETROCHEMICAL INDUSTRIES LTD. (JA) 1978-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240408216-A1 PROTEIN INHIBITOR OR DEGRADING AGENT, PHARMACEUTICAL COMPOSITION CONTAINING SAME AND PHARMACEUTICAL USE PSME1, IDE, PRUNE1 MAPT 388/4885GAA 250/4885LMNA 1363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.