SCHEMBL29690180

SCHEMBL29690180

COc1cc(CN2CCNCC2)c(OC)cc1Br

nearest known ligand 0.64

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.55
CHRM2 P08172 1/20 0.55
SLC6A4 P31645 1/20 0.55
OPRD1 P41143 1/20 0.55
OPRK1 P41145 1/20 0.55
HTR2A P28223 6/20 0.54
APOBEC3A P31941 1/20 0.54
CTDSP1 Q9GZU7 1/20 0.54
APOBEC3G Q9HC16 1/20 0.54
MAPK1 P28482 1/20 0.52
KDM4E B2RXH2 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
HTR2C P28335 2/20 0.47
TAAR1 Q96RJ0 2/20 0.47
HTR2B P41595 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20545632 1.00 CYP1A2 (0.55) CYP1A2CHRM2SLC6A4OPRD1OPRK1
Hydrochloric Acid SCHEMBL27837634 0.86 KDM4E (0.63) CYP1A2CHRM2SLC6A4OPRD1OPRK1
SCHEMBL19869945 0.83 GAA (0.63) HTR2AMAPK1KDM4ETDP1HTR2C
SCHEMBL17931046 0.82 CXCR4 (0.55) CYP1A2CHRM2SLC6A4OPRD1OPRK1
SCHEMBL22471551 0.82 ALDH1A1 (0.60) CYP1A2CHRM2SLC6A4OPRD1OPRK1
SCHEMBL19869933 0.78 CYP1A2 (0.50) CYP1A2CHRM2SLC6A4OPRD1OPRK1
SCHEMBL1714907 0.76 SLC6A4 (0.62) CYP1A2CHRM2SLC6A4OPRD1OPRK1
SCHEMBL22542166 0.76 CYP1A2 (0.62) CYP1A2CHRM2SLC6A4OPRD1OPRK1
SCHEMBL19869944 0.76 KDM4E (0.55) HTR2AMAPK1KDM4EHTR2CTAAR1
SCHEMBL7300721 0.76 CYP1A2 (0.62) CYP1A2CHRM2SLC6A4OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106796-A1 SYSTEM AND METHOD FOR THE TREATMENT OF TELOGEN EFFLUVIUM, ANDROGENETIC ALOPECIA, AND OTHER HAIR LOSS DISORDERS FOLLEA INTERNATIONAL (US) 2026-05-21 WO disclosed
US-20260041652-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA FOLLEA INT (US) 2026-02-12 US disclosed
US-20250367232-A1 HALOGEN TREATMENT OF HEART ATTACK AND ISCHEMIC INJURY HUTCHINSON FRED CANCER RES (US) 2025-12-04 US disclosed
CN-118756156-A Method for preparing deuterated cyclic compound 无锡绿能电合科技有限公司 2024-10-11 CN disclosed
US-12016880-B2 Halogen treatment of heart attack and ischemic injury FRED HUTCHINSON CANCER CENTER (US) 2024-06-25 US disclosed
WO-2024107708-A1 TAAR RECEPTOR AGONISTS FOR SEXUAL DYSFUNCTION ReJoy (US) 2024-05-23 WO disclosed
EP-3104939-B1 TREATMENT OF HEART ATTACK AND ISCHEMIC INJURY WITH SODIUM IODIDE FRED HUTCHINSON CANCER CENTER (US) 2024-05-01 EP disclosed
US-20220313730-A1 HALOGEN TREATMENT OF HEART ATTACK AND ISCHEMIC INJURY FRED HUTCHINSON CANCER CENTER 2022-10-06 US disclosed
US-11383084-B2 Treatment of dermatological conditions via neuromodulation PALO ALTO INVESTORS (US) 2022-07-12 US disclosed
US-11337937-B2 TARR receptor agonists for sexual dysfunction JOHN MCCOY 2022-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041652-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA DYRK4, DYRK2, STRA6 CYP1A2 3368/4885CHRM2 2954/4885SLC6A4 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.