Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL298691 | 0.91 | ESR2 (0.56) | ESR1ESR2CCR2AKR1C1AKR1C3 | |
| SCHEMBL297426 | 0.85 | ESR1 (0.50) | ESR1ESR2CCR2AKR1C1AKR1C2 | |
| SCHEMBL296906 | 0.84 | ESR1 (0.59) | ESR1ESR2CYP3A4TSHRALDH1A1 | |
| SCHEMBL30060373 | 0.81 | ESR1 (0.57) | ESR1ESR2CCR2CYP3A4CYP2D6 | |
| SCHEMBL297639 | 0.81 | ESR1 (0.57) | ESR1ESR2CCR2CYP3A4CYP2D6 | |
| SCHEMBL297024 | 0.79 | ESR1 (0.54) | ESR1ESR2MAOA | |
| SCHEMBL4760757 | 0.78 | ESR2 (0.48) | ESR1ESR2CCR2CYP2D6MAOA | |
| SCHEMBL297177 | 0.76 | ESR1 (0.50) | ESR1ESR2ALDH1A1 | |
| SCHEMBL297898 | 0.76 | ESR1 (0.50) | ESR1ESR2 | |
| SCHEMBL296382 | 0.75 | ESR1 (0.63) | ESR1ESR2TSHRALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 317 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763560-A1 | POLYARYLATE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2007-03-21 | — | — | EP | claimed |
| US-7109274-B2 | Polyarylate compositions | GENERAL ELECTRIC COMPANY (US) | 2006-09-19 | — | — | US | claimed |
| WO-2006012161-A1 | POLYARYLATE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2006-02-02 | — | — | WO | claimed |
| US-20060004152-A1 | Polyarylate compositions | GENERAL ELECTRIC COMPANY | 2006-01-05 | — | — | US | claimed |
| EP-1560871-A1 | METHOD FOR MAKING COPOLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 2005-08-10 | — | — | EP | claimed |
| WO-2004041907-A1 | METHOD FOR MAKING COPOLYCARBONATES | GENERAL ELECTRIC COMPANY (US) | 2004-05-21 | — | — | WO | claimed |
| US-6657038-B1 | Melt condensation copolymerization of dihydroxyaromatic compounds and diphenyl carbonate derivative in presence of metal hydroxide and quaternary phosphonium salt | GENERAL ELECTRIC COMPANY | 2003-12-02 | — | — | US | claimed |
| US-6576739-B2 | Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups | GENERAL ELECTRIC COMPANY | 2003-06-10 | — | — | US | claimed |
| US-20020111456-A1 | Method of polycarbonate preparation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-08-15 | — | — | US | claimed |
| WO-2001085825-A2 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2001-11-15 | — | — | WO | claimed |
| US-11898025-B2 | Polyethylene with additives for increased environmental stress crack resistance | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2024-02-13 | — | — | US | disclosed |
| US-11535732-B2 | Polyethylene with polycarbonate-siloxane for increased environmental stress crack resistance | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2022-12-27 | — | — | US | disclosed |
| US-20210388189-A1 | POLYETHYLENE WITH ADDITIVES FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-12-16 | — | — | US | disclosed |
| US-20210309839-A1 | POLYETHYLENE WITH POLYCARBONATE-SILOXANE FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2021-10-07 | — | — | US | disclosed |
| EP-3877463-A1 | POLYETHYLENE WITH ADDITIVES FOR INCREASED ENVIRONMENTAL STRESS CRACK RESISTANCE | SABIC Global Technologies B.V. (NL) | 2021-09-15 | — | — | EP | disclosed |
| US-20020111456-A1 | Method of polycarbonate preparation | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2002-08-15 | — | — | US | disclosed |
| US-6420512-B1 | SCREW EXTRUSION AND ESTER INTERCHANGE | GENERAL ELECTRIC COMPANY | 2002-07-16 | — | — | US | disclosed |
| US-20020035234-A1 | Continuous preparation of polycarbonate | GENERAL ELECTRIC COMPANY | 2002-03-21 | — | — | US | disclosed |
| WO-2002008311-A2 | CONTINUOUS PREPARATION OF POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2002-01-31 | — | — | WO | disclosed |
| WO-2001085825-A2 | METHOD OF POLYCARBONATE PREPARATION | GENERAL ELECTRIC COMPANY (US) | 2001-11-15 | — | — | WO | disclosed |