Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.32 |
| ▸ | CES1 | P23141 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | F12 | P00748 | 1/20 | 0.30 |
| ▸ | F7 | P08709 | 1/20 | 0.30 |
| ▸ | F3 | P13726 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10320219 | 0.67 | MAPT (0.33) | TSHRALDH1A1MEN1KMT2AF2 | |
| Hydrochloric Acid SCHEMBL7944168 | 0.66 | ATM (0.34) | TSHRALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL25267928 | 0.62 | CES1 (0.38) | CES2CES1TSHRDAONAPRT | |
| Hydrochloric Acid SCHEMBL30298007 | 0.61 | CES2 (0.32) | CES2CES1TSHRDAONAPRT | |
| Hydrochloric Acid SCHEMBL29690902 | 0.61 | CES2 (0.32) | CES2CES1TSHRDAONAPRT | |
| Hydrochloric Acid SCHEMBL29690727 | 0.61 | CES2 (0.32) | CES2CES1TSHRDAONAPRT | |
| SCHEMBL27270228 | 0.61 | CES1 (0.36) | CES2CES1TSHRDAONAPRT | |
| SCHEMBL27275221 | 0.61 | CES1 (0.36) | CES2CES1TSHRDAONAPRT | |
| SCHEMBL27266873 | 0.61 | CES1 (0.36) | CES2CES1TSHRDAONAPRT | |
| SCHEMBL13985061 | 0.59 | MAPT (0.47) | CES2CES1TSHRDAONAPRT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122080535-A | Propylene-based copolymer pellet composition and preparation method and application thereof | — | 2026-05-26 | — | — | CN | disclosed |
| CN-112759680-B | Olefin polymerization catalyst component, olefin polymerization catalyst and application | 中国石油化工股份有限公司 | 2022-05-24 | — | — | CN | disclosed |