SCHEMBL2969153

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13042076	0.91	PPARG (0.42)	AKR1B1CYP19A1PPARGPPARACYP2C9
	SCHEMBL2985001	0.89	SRD5A2 (0.40)	AKR1B1CYP19A1PPARGPPARATP53
	SCHEMBL13994485	0.84	PPARG (0.43)	AKR1B1PPARGPPARATP53
	SCHEMBL13042084	0.81	TP53 (0.40)	PPARGPPARATP53CYP2C9EGFR
	SCHEMBL2975766	0.77	TP53 (0.60)	TP53CYP2C9MAPT
	SCHEMBL2984500	0.77	PPARG (0.51)	PPARGPPARACYP2C9EGFRCHRM4
	SCHEMBL2982129	0.77	SRD5A2 (0.35)	AKR1B1CYP19A1PPARGPPARA
	SCHEMBL13994578	0.77	TBXAS1 (0.36)	AKR1B1PPARGPPARAMAPT
	SCHEMBL2982133	0.77	SRD5A2 (0.35)	AKR1B1CYP19A1PPARGPPARA
	SCHEMBL13994484	0.77	TBXAS1 (0.36)	AKR1B1PPARGPPARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.