Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 7/20 | 0.54 |
| ▸ | CHUK | O15111 | 4/20 | 0.46 |
| ▸ | IKBKB | O14920 | 3/20 | 0.46 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | GAK | O14976 | 1/20 | 0.36 |
| ▸ | STK16 | O75716 | 1/20 | 0.36 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24600622 | 1.00 | ENPP1 (0.54) | ENPP1CHUKIKBKBENPP3CA12 | |
| SCHEMBL24600558 | 0.86 | ENPP1 (0.56) | ENPP1CHUKIKBKBENPP3CA12 | |
| SCHEMBL29691620 | 0.86 | ENPP1 (0.56) | ENPP1CHUKIKBKBENPP3CA12 | |
| SCHEMBL29248817 | 0.85 | NUDT1 (0.41) | ENPP1CHUKIKBKBENPP3NUDT1 | |
| SCHEMBL24600967 | 0.83 | PRKCI (0.47) | CHUKIKBKBNUDT1INSRMAPK8 | |
| SCHEMBL24600623 | 0.83 | NUDT1 (0.40) | ENPP1CHUKIKBKBNUDT1INSR | |
| Hydrochloric Acid SCHEMBL29691611 | 0.82 | PRKCI (0.47) | CHUKIKBKBNUDT1INSRMAPK8 | |
| Hydrochloric Acid SCHEMBL26679985 | 0.82 | PRKCI (0.47) | CHUKIKBKBNUDT1INSRMAPK8 | |
| SCHEMBL26679905 | 0.82 | NUDT1 (0.40) | ENPP1CHUKIKBKBNUDT1INSR | |
| SCHEMBL29691588 | 0.81 | ENPP1 (0.53) | ENPP1CHUKIKBKBCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022146022-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | 주식회사 티씨노바이오사이언스 | 2022-07-07 | — | — | WO | claimed |
| WO-2022146022-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | 주식회사 티씨노바이오사이언스 | 2022-07-07 | — | — | WO | disclosed |