Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | NUDT1 | P36639 | 7/20 | 0.44 |
| ▸ | CHUK | O15111 | 2/20 | 0.43 |
| ▸ | INSR | P06213 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.39 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29691611 | 0.99 | PRKCI (0.47) | PRKCIEGFRNUDT1CHUKINSR | |
| Hydrochloric Acid SCHEMBL26679985 | 0.99 | PRKCI (0.47) | PRKCIEGFRNUDT1CHUKINSR | |
| SCHEMBL24600503 | 0.87 | PRKCI (0.43) | PRKCINUDT1CHUKINSRMAPK8 | |
| Hydrochloric Acid SCHEMBL26679823 | 0.85 | PRKCI (0.42) | PRKCICHUKINSRMAPK8CAMKK2 | |
| Hydrochloric Acid SCHEMBL29691541 | 0.85 | PRKCI (0.42) | PRKCICHUKINSRMAPK8CAMKK2 | |
| SCHEMBL24600623 | 0.84 | NUDT1 (0.40) | PRKCINUDT1CHUKINSRMAPK8 | |
| SCHEMBL24600622 | 0.83 | ENPP1 (0.54) | PRKCINUDT1CHUKINSRMAPK8 | |
| SCHEMBL29691600 | 0.83 | ENPP1 (0.54) | PRKCINUDT1CHUKINSRMAPK8 | |
| SCHEMBL26679905 | 0.83 | NUDT1 (0.40) | PRKCINUDT1CHUKINSRMAPK8 | |
| SCHEMBL24600955 | 0.83 | CDK9 (0.47) | PRKCIEGFRNUDT1CHUKMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276100-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | Txinno Bioscience Inc. (KR) | 2023-11-15 | — | — | EP | disclosed |
| CN-116669726-A | Novel naphthyridinone derivatives having inhibitory activity against exonuclease-phosphodiesterase and use thereof | 谛希诺生物科技有限公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2022146022-A1 | NOVEL NAPHTHYRIDINONE DERIVATIVE HAVING INHIBITORY ACTIVITY AGAINST ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE AND USE THEREOF | 주식회사 티씨노바이오사이언스 | 2022-07-07 | — | — | WO | disclosed |