SCHEMBL29691750

SCHEMBL29691750

C[C@H](NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)CN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CAPN1 P07384 8/20 0.54
▸ CTSB P07858 3/20 0.49
▸ APLNR P35414 1/20 0.43
▸ OPRM1 P35372 1/20 0.40
▸ OPRD1 P41143 1/20 0.40
▸ CALCRL Q16602 3/20 0.39
▸ GRB2 P62993 1/20 0.39
▸ BDKRB2 P30411 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29554458 0.99 CAPN1 (0.54) CAPN1CTSBAPLNROPRM1OPRD1
SCHEMBL30647293 0.95 CAPN1 (0.54) CAPN1CTSBAPLNROPRM1OPRD1
SCHEMBL30712732 0.94 CAPN1 (0.47) CAPN1CTSBAPLNROPRM1OPRD1
SCHEMBL31750671 0.94 CAPN1 (0.47) CAPN1CTSBAPLNROPRM1OPRD1
SCHEMBL29691873 0.94 CAPN1 (0.47) CAPN1CTSBAPLNROPRM1OPRD1
SCHEMBL31259022 0.93 CAPN1 (0.52) CAPN1CTSBAPLNROPRM1OPRD1
SCHEMBL29554130 0.93 CAPN1 (0.47) CAPN1CTSBAPLNROPRM1OPRD1
SCHEMBL29760912 0.91 CAPN1 (0.54) CAPN1CTSBAPLNROPRM1OPRD1
SCHEMBL31751216 0.90 OPRM1 (0.43) CAPN1CTSBAPLNROPRM1OPRD1
SCHEMBL29760883 0.90 CAPN1 (0.55) CAPN1CTSBOPRM1OPRD1BDKRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724471-A1 GLP-1/GIP DUAL, GLP-1/GCG DUAL AND GLP-1/GIP/GCG TRIPLE RECEPTOR AGONISTS Sun Pharmaceutical Industries Limited (IN) 2026-04-15 — — EP claimed
WO-2025264809-A1 CHEMICALLY MODIFIED PEPTIDES AND USE THEREOF NEUROCRINE BIOSCIENCES, INC. (US) 2025-12-26 — — WO claimed
WO-2024252366-A1 GLP-1/GIP DUAL, GLP-1/GCG DUAL AND GLP-1/GIP/GCG TRIPLE RECEPTOR AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2024-12-12 — — WO claimed
US-11352405-B2 GLP-1/glucagon receptor agonists in the treatment of fatty liver disease and steatohepatitis SANOFI (FR) 2022-06-07 — — US claimed
EP-4724471-A1 GLP-1/GIP DUAL, GLP-1/GCG DUAL AND GLP-1/GIP/GCG TRIPLE RECEPTOR AGONISTS Sun Pharmaceutical Industries Limited (IN) 2026-04-15 — — EP disclosed
WO-2025264809-A1 CHEMICALLY MODIFIED PEPTIDES AND USE THEREOF NEUROCRINE BIOSCIENCES, INC. (US) 2025-12-26 — — WO disclosed
WO-2025019280-A1 DELIVERY SYSTEM FOR TWO OR MORE AUTOINJECTORS TEVA BRANDED PHARMACEUTICAL PRODUCTS R&D, INC. (US) 2025-01-23 — — WO disclosed
WO-2024252366-A1 GLP-1/GIP DUAL, GLP-1/GCG DUAL AND GLP-1/GIP/GCG TRIPLE RECEPTOR AGONISTS SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2024-12-12 — — WO disclosed
EP-4358996-A1 TREATMENT OF CONGENITAL HYPERINSULINISM WITH AVEXITIDE Eiger Biopharmaceuticals, Inc. (US) 2024-05-01 — — EP disclosed
US-20230364194-A1 GLP-1R/GCGR Dual Target Agonist Polypeptide Derivative for Treatment of Hepatic Fibrosis Associated with Viral Hepatitis SHENZHEN TURIER BIOTECH CO., LTD. (CN) 2023-11-16 — — US disclosed
US-20230183310-A1 Polypeptide Compounds and Use Thereof in the Prevention or Treatment of Diabetes or Diabetic Complications SHENZHEN TURIER BIOTECH CO., LTD (CN) 2023-06-15 — — US disclosed
EP-3664833-B1 GLP-1/GLUCAGON RECEPTOR AGONISTS IN THE TREATMENT OF FATTY LIVER DISEASE AND STEATOHEPATITIS SANOFI SA (FR) 2023-05-31 — — EP disclosed
WO-2022271753-A1 TREATMENT OF CONGENITAL HYPERINSULINISM WITH AVEXITIDE EIGER BIOPHARMACEUTICALS, INC. (US) 2022-12-29 — — WO disclosed
US-11419918-B2 Treatment of biliary cirrhosis based on oxyntomodulin analogue GLP-1R/GCGR dual-target agonist peptide SHENZHEN TURIER BIOTECH CO., LTD. 2022-08-23 — — US disclosed
US-11352405-B2 GLP-1/glucagon receptor agonists in the treatment of fatty liver disease and steatohepatitis SANOFI (FR) 2022-06-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183310-A1 Polypeptide Compounds and Use Thereof in the Prevention or Treatment of Diabetes or Diabetic Complications IAPP, PNLIP, DPP4 CAPN1 2127/4885CTSB 110/4885APLNR 247/4885
US-11419918-B2 Treatment of biliary cirrhosis based on oxyntomodulin analogue GLP-1R/GCGR dual-target agonist peptide GCGR, GLP1R, GIPR CAPN1 2190/4885CTSB 751/4885APLNR 337/4885
US-20230364194-A1 GLP-1R/GCGR Dual Target Agonist Polypeptide Derivative for Treatment of Hepatic Fibrosis Associated with Viral Hepatitis GLP1R, GCGR, GIPR CAPN1 3687/4885CTSB 372/4885APLNR 214/4885
US-11352405-B2 GLP-1/glucagon receptor agonists in the treatment of fatty liver disease and steatohepatitis GLP1R, GCGR, GIPR CAPN1 4524/4885CTSB 1945/4885APLNR 175/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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