Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 4/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.32 |
| ▸ | CPB1 | P15086 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30634622 | 0.91 | CPB2 (0.34) | SMN1; SMN2CPB2CPB1 | |
| SCHEMBL31146592 | 0.87 | MME (0.34) | MMECPB2CPB1CA1CA2 | |
| SCHEMBL3138900 | 0.84 | CPB2 (0.33) | SMN1; SMN2MMECPB2CPB1 | |
| SCHEMBL15101094 | 0.84 | KDM4E (0.30) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL16770241 | 0.84 | ACE (0.40) | KDM4EMAPTTHRBALOX15NFKB1 | |
| SCHEMBL8526485 | 0.84 | CPB2 (0.34) | CPB2CPB1 | |
| SCHEMBL8526486 | 0.84 | CPB2 (0.34) | CPB2CPB1 | |
| SCHEMBL4292046 | 0.83 | CPB2 (0.33) | SMN1; SMN2MMECPB2CPB1 | |
| SCHEMBL4292047 | 0.83 | CPB2 (0.33) | SMN1; SMN2MMECPB2CPB1 | |
| SCHEMBL31359131 | 0.83 | CPB2 (0.32) | CPB2CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025002339-A1 | NOVEL ENGINEERED LYASE AND USE THEREOF | 上海赛增医疗科技有限公司 | 2025-01-02 | — | — | WO | claimed |
| EP-3252068-B1 | METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION USING OLIGONUCLEOTIDE BASED DRUGS ADMINISTERED IN VIVO OR IN VITRO | SMITH LARRY J (US) | 2025-07-02 | — | — | EP | disclosed |
| US-12319914-B2 | Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro | SMITH LARRY J (US) | 2025-06-03 | — | — | US | disclosed |
| WO-2025002339-A1 | NOVEL ENGINEERED LYASE AND USE THEREOF | 上海赛增医疗科技有限公司 | 2025-01-02 | — | — | WO | disclosed |
| CN-115181279-B | Fluorescent metal-organic framework material for detecting biomarker 3-nitrotyrosine of human body and application thereof | 渤海大学 | 2023-05-12 | — | — | CN | disclosed |
| EP-4089169-A1 | METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION USING OLIGONUCLEOTIDE BASED DRUGS ADMINISTERED IN VIVO OR IN VITRO | Smith, Larry J. (US) | 2022-11-16 | — | — | EP | disclosed |
| US-20220290150-A1 | METHODS AND COMPOSITIONS FOR MODULATING GENE EXPRESSION USING OLIGONUCLEOTIDE BASED DRUGS ADMINISTERED IN VIVO OR IN VITRO | SMITH LARRY J (US) | 2022-09-15 | — | — | US | disclosed |
| CN-114660028-A | Method for detecting melamine by fluorescence lateral flow chromatography based on gold nano-cluster aggregation induction enhancement | 江南大学 | 2022-06-24 | — | — | CN | disclosed |
| US-11359201-B2 | Methods and compositions for modulating gene expression using oligonucleotide based drugs administered in vivo or in vitro | SMITH LARRY J (US) | 2022-06-14 | — | — | US | disclosed |