Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 11/20 | 0.53 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371600 | 1.00 | MET (0.53) | METCSNK1DCSF1RRETPDGFRB | |
| SCHEMBL371920 | 0.87 | MET (0.60) | METCSNK1DCSF1RRETPDGFRB | |
| SCHEMBL29693525 | 0.87 | MET (0.62) | METCSNK1DKDR | |
| SCHEMBL371540 | 0.87 | MET (0.62) | METCSNK1DKDR | |
| SCHEMBL371825 | 0.82 | MET (0.76) | METCSNK1DCSF1RPDGFRBKIT | |
| SCHEMBL371541 | 0.78 | MET (0.46) | METKDR | |
| SCHEMBL371622 | 0.78 | MET (0.64) | METKDR | |
| SCHEMBL2189472 | 0.78 | MET (0.87) | METCSNK1DCSF1RPDGFRBKIT | |
| SCHEMBL15580183 | 0.77 | MET (0.65) | METCSNK1DPDGFRBKITPDGFRA | |
| SCHEMBL20525805 | 0.76 | RIPK1 (0.55) | METCSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329918-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2022-05-25 | — | — | EP | disclosed |