Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4576177 | 1.00 | MLYCD (0.60) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL1052230 | 0.88 | MLYCD (0.63) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL31173731 | 0.88 | MLYCD (0.63) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL15682652 | 0.87 | MLYCD (0.59) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL15682773 | 0.86 | MLYCD (0.62) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL17231401 | 0.85 | MLYCD (0.60) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL24713109 | 0.84 | MLYCD (0.67) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL25779257 | 0.84 | MTOR (0.55) | MLYCDRPS6KB1AURKA | |
| SCHEMBL30661718 | 0.83 | MLYCD (0.65) | MLYCDMEN1KMT2APLA2G1BCYP1A2 | |
| SCHEMBL13884195 | 0.82 | L3MBTL1 (0.64) | MLYCDMEN1KMT2APLA2G1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3329918-B1 | C-MET MODULATORS AND METHODS OF USE | EXELIXIS INC (US) | 2022-05-25 | — | — | EP | disclosed |