Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.43 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.37 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29445654 | 0.81 | NR3C1 (0.37) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| SCHEMBL29445652 | 0.80 | NR3C1 (0.37) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| Ammonia Solution, Strong SCHEMBL28709962 | 0.80 | NR3C1 (0.37) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| SCHEMBL29695764 | 0.75 | CHEK1 (0.41) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| SCHEMBL3033771 | 0.72 | TUBB4A (0.37) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| SCHEMBL1701230 | 0.70 | CHEK1 (0.46) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| SCHEMBL9210022 | 0.70 | MAPT (0.52) | NR3C1CYP11B1CYP11B2PGRSMN1; SMN2 | |
| SCHEMBL13836976 | 0.70 | CHEK1 (0.50) | CHEK1AURKADAPK3CSNK1A1GSK3A | |
| SCHEMBL18298354 | 0.68 | RPS6KA5 (0.40) | CSNK1A1CLK4RPS6KA5SMN1; SMN2 | |
| SCHEMBL21295429 | 0.67 | NR3C1 (0.54) | CHEK1AURKADAPK3CSNK1A1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903618-B1 | RHO KINASE INHIBITORS | KADMON CORP LLC (US) | 2022-06-01 | — | — | EP | disclosed |