Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL29695902

Clc1ccc(COc2cccc(NC3CCNCC3)n2)nc1.O=C(O)C(F)(F)F

nearest known ligand 0.47

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 2/20 0.47
HRH3 Q9Y5N1 2/20 0.47
IRAK4 Q9NWZ3 8/20 0.42
FLT3 P36888 2/20 0.42
IRAK1 P51617 2/20 0.42
LCK P06239 1/20 0.42
RET P07949 1/20 0.42
PDGFRB P09619 1/20 0.42
CDK7 P50613 1/20 0.42
BLK P51451 1/20 0.42
CCNH P51946 1/20 0.42
CCNT1 O60563 6/20 0.40
CDK4 P11802 1/20 0.39
CDK2 P24941 1/20 0.39
CDK5 Q00535 1/20 0.39
NRAS P01111 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
GRM2 Q14416 1/20 0.36
GRM3 Q14832 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL29928889 0.95 HRH4 (0.49) HRH4HRH3IRAK4FLT3IRAK1
SCHEMBL23383324 0.91 IRAK4 (0.49) HRH3IRAK4FLT3IRAK1LCK
SCHEMBL23383280 0.85 FLT3 (0.51) IRAK4FLT3IRAK1LCKRET
Trifluoroacetic Acid SCHEMBL30404349 0.84 GLP1R (0.42) GRM2GRM3
Trifluoroacetic Acid SCHEMBL25272721 0.84 GLP1R (0.42) GRM2GRM3
Trifluoroacetic Acid SCHEMBL29928598 0.82 F10 (0.43) HRH4HRH3FLT3CDK4CDK2
Trifluoroacetic Acid SCHEMBL29586524 0.79 HRH4 (0.49) HRH4HRH3IRAK4FLT3IRAK1
SCHEMBL23361963 0.77 CCNT1 (0.49) CCNT1
Trifluoroacetic Acid SCHEMBL29928577 0.77 HRH4 (0.41) HRH4HRH3FLT3
SCHEMBL24848620 0.77 IRAK4 (0.51) HRH3IRAK4FLT3IRAK1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002348-A1 GLP-1 Receptor Agonist and Use Thereof ILDONG PHARMACEUTICAL CO., LTD. (KR) 2023-01-05 US disclosed
EP-4059929-A1 GLP-1 RECEPTOR AGONIST AND USE THEREOF Ildong Pharmaceutical Co., Ltd. (KR) 2022-09-21 EP disclosed
CN-114728940-A GLP-1 receptor agonists and uses thereof 日东制药株式会社 2022-07-08 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230002348-A1 GLP-1 Receptor Agonist and Use Thereof GLP1R, GIPR, GPR119 HRH4 1194/4885HRH3 1856/4885IRAK4 1953/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.