Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | DAO | P14920 | 1/20 | 0.57 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL21357656 | 0.92 | TSHR (0.70) | TSHRTP53DAONAPRTSRD5A2 | |
| Benzoic Acid SCHEMBL28400772 | 0.90 | TSHR (0.67) | TSHRTP53DAONAPRTSRD5A2 | |
| Benzoic Acid SCHEMBL28203619 | 0.90 | TSHR (0.67) | TSHRTP53DAONAPRTSRD5A2 | |
| 4-Chloro-Benzoic Acid SCHEMBL27968681 | 0.89 | TSHR (0.71) | TSHRTP53DAONAPRTSRD5A2 | |
| Furan SCHEMBL28115721 | 0.84 | TSHR (0.46) | TSHRTP53DAONAPRTSRD5A2 | |
| Terephthalic Acid SCHEMBL21443891 | 0.83 | TSHR (0.92) | TSHRTP53DAONAPRTSRD5A2 | |
| Terephthalic Acid SCHEMBL11040866 | 0.80 | TSHR (0.86) | TSHRTP53DAONAPRTSRD5A2 | |
| Terephthalic Acid SCHEMBL9250012 | 0.80 | TSHR (0.86) | TSHRTP53DAONAPRTSRD5A2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.80 | TSHR (1.00) | TSHRTP53DAONAPRTSRD5A2 | |
| Terephthalic Acid SCHEMBL175823 | 0.80 | TSHR (1.00) | TSHRTP53DAONAPRTSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591606-B | Fast crystallization polyester composite material, molding compound product, preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2023-02-17 | — | — | CN | disclosed |
| CN-114591606-A | Fast crystallization polyester composite material, molding compound product, preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2022-06-07 | — | — | CN | disclosed |