Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.92 |
| ▸ | TP53 | P04637 | 1/20 | 0.92 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.80 |
| ▸ | DAO | P14920 | 1/20 | 0.80 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.75 |
| ▸ | CES2 | O00748 | 1/20 | 0.72 |
| ▸ | CES1 | P23141 | 1/20 | 0.72 |
| ▸ | CA1 | P00915 | 2/20 | 0.71 |
| ▸ | CA2 | P00918 | 2/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA3 | P07451 | 1/20 | 0.71 |
| ▸ | TYR | P14679 | 1/20 | 0.71 |
| ▸ | DRD1 | P21728 | 1/20 | 0.71 |
| ▸ | CA4 | P22748 | 1/20 | 0.71 |
| ▸ | CA6 | P23280 | 1/20 | 0.71 |
| ▸ | CA5A | P35218 | 1/20 | 0.71 |
| ▸ | CA7 | P43166 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL9250012 | 0.96 | TSHR (0.86) | TSHRTP53NAPRTDAOSRD5A2 | |
| Terephthalic Acid SCHEMBL1655 | 0.96 | TSHR (1.00) | TSHRTP53NAPRTDAOSRD5A2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.96 | TSHR (1.00) | TSHRTP53NAPRTDAOSRD5A2 | |
| Terephthalic Acid SCHEMBL175823 | 0.96 | TSHR (1.00) | TSHRTP53NAPRTDAOSRD5A2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.96 | TSHR (1.00) | TSHRTP53NAPRTDAOSRD5A2 | |
| Terephthalic Acid SCHEMBL4961359 | 0.93 | TSHR (0.93) | TSHRTP53NAPRTDAOSRD5A2 | |
| Terephthalic Acid SCHEMBL25381766 | 0.92 | TSHR (0.92) | TSHRTP53NAPRTDAOSRD5A2 | |
| Terephthalic Acid SCHEMBL17667155 | 0.92 | TSHR (0.92) | TSHRTP53NAPRTDAOSRD5A2 | |
| Terephthalic Acid SCHEMBL20704876 | 0.92 | TSHR (0.92) | TSHRTP53NAPRTDAOSRD5A2 | |
| Terephthalic Acid SCHEMBL156613 | 0.92 | TSHR (0.92) | TSHRTP53NAPRTDAOSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114694886-A | Impact-resistant corrosion-resistant fireproof cable and preparation method thereof | 刘新官 | 2022-07-01 | — | — | CN | claimed |
| CN-103464013-B | High-performance hybrid separation membrane and preparation method thereof | YANTAI LVSHUIFU MEMBRANE MATERIAL LTD | 2014-11-05 | — | — | CN | claimed |
| CN-103463999-B | Preparation method of ultrathin salt-cutting separation membrane | YANTAI LVSHUIFU MEMBRANE MATERIAL LTD. (CN) | 2014-10-22 | — | — | CN | claimed |
| CN-103480278-A | Preparation method and application of anti-pollution hydrophilic separating membrane | YANTAI LVSHUIFU MEMBRANE MATERIAL LTD | 2014-01-01 | — | — | CN | claimed |
| CN-103463999-A | Preparation method of novel ultrathin salt-cutting separation membrane | YANTAI LVSHUIFU MEMBRANE MATERIAL LTD | 2013-12-25 | — | — | CN | claimed |
| CN-103464013-A | High-performance hybrid separation membrane and preparation method thereof | YANTAI LVSHUIFU MEMBRANE MATERIAL LTD | 2013-12-25 | — | — | CN | claimed |
| CN-103418250-A | Method of in-situ generation of nano particle on separating membrane surface | YANTAI LVSHUIFU MEMBRANE MATERIAL LTD | 2013-12-04 | — | — | CN | claimed |
| CN-103194048-A | Flame retardant compositions, molded products and fiber matrixes | DU PONT | 2013-07-10 | — | — | CN | claimed |
| CN-102637879-A | Micro-nano-structure anode material for Li-air battery and preparation method of micro-nano-structure anode material | UNIV CENTRAL SOUTH | 2012-08-15 | — | — | CN | claimed |
| CN-102149450-A | Water purification membranes with improved fouling resistance | UNIV TEXAS | 2011-08-10 | — | — | CN | claimed |
| CN-101351502-A | Polymer alloy composition | CHEIL IND INC (KR) | 2009-01-21 | — | — | CN | claimed |
| CN-101338189-A | High voltage electrospinning method for preparing multi-fluorescence-encoded micro-beads | UNIV JILIN (CN) | 2009-01-07 | — | — | CN | claimed |
| CN-119662244-A | Colorimetric-luminescent dual-mode probe for copper ion detection and preparation method and application thereof | 辽宁大学 | 2025-03-21 | — | — | CN | disclosed |
| WO-2023171792-A1 | MODIFIED POLYESTER-BASED ELASTOMER AND METHOD FOR PRODUCING SAME | ＭＣＰＰイノベーション合同会社 | 2023-09-14 | — | — | WO | disclosed |
| CN-115322542-B | Polylactic acid/polycaprolactone/talcum powder composite material and preparation method thereof | 宁波大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-114694886-A | Impact-resistant corrosion-resistant fireproof cable and preparation method thereof | 刘新官 | 2022-07-01 | — | — | CN | disclosed |
| CN-100539271-C | Solid polymer electrolyte membrane and method for producing same | ASAHI CHEMICAL CORP (JP) | 2009-09-09 | — | — | CN | disclosed |
| CN-101351502-A | Polymer alloy composition | CHEIL IND INC (KR) | 2009-01-21 | — | — | CN | disclosed |
| CN-101338189-A | High voltage electrospinning method for preparing multi-fluorescence-encoded micro-beads | UNIV JILIN (CN) | 2009-01-07 | — | — | CN | disclosed |
| CN-101015081-A | Solid polymer electrolyte membrane and method for producing same | ASAHI CHEMICAL CORP (JP) | 2007-08-08 | — | — | CN | disclosed |