Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728318 | 1.00 | LMNA (0.57) | LMNAKMT2ACHRNA7KDM4EALDH1A1 | |
| SCHEMBL31516755 | 0.78 | KDM4E (0.58) | LMNAKMT2ACHRNA7KDM4EALDH1A1 | |
| SCHEMBL2067481 | 0.78 | LMNA (0.57) | LMNAKMT2ACHRNA7KDM4EALDH1A1 | |
| SCHEMBL22925970 | 0.78 | LMNA (0.57) | LMNAKMT2ACHRNA7KDM4EALDH1A1 | |
| SCHEMBL861501 | 0.78 | LMNA (0.61) | LMNAKMT2ACHRNA7KDM4EALDH1A1 | |
| SCHEMBL3462062 | 0.78 | LMNA (0.57) | LMNAKMT2ACHRNA7KDM4EALDH1A1 | |
| SCHEMBL3155897 | 0.78 | LMNA (0.57) | LMNAKMT2ACHRNA7KDM4EALDH1A1 | |
| SCHEMBL46317 | 0.78 | KDM4E (0.58) | LMNAKMT2ACHRNA7KDM4EALDH1A1 | |
| SCHEMBL4191891 | 0.78 | LMNA (0.57) | LMNAKMT2ACHRNA7KDM4EALDH1A1 | |
| SCHEMBL17159482 | 0.77 | LMNA (0.53) | LMNAKMT2ACHRNA7KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4004001-B1 | SUBSTITUTED PYRIMIDINEDIONE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2025-09-03 | — | — | EP | disclosed |
| CN-116547274-A | MAGL inhibitors | H.隆德贝克有限公司 | 2023-08-04 | — | — | CN | disclosed |
| US-20220267347-A1 | SUBSTITUTED PYRIMIDINEDIONE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-08-25 | — | — | US | disclosed |
| EP-4004001-A1 | SUBSTITUTED PYRIMIDINEDIONE COMPOUNDS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267347-A1 | SUBSTITUTED PYRIMIDINEDIONE COMPOUNDS AND USES THEREOF | GNRHR, CDK20, PGR | LMNA 1070/4885KMT2A 1921/4885CHRNA7 2823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.