Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 17/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 15/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 7/20 | 0.51 |
| ▸ | KDM4A | O75164 | 3/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16150881 | 1.00 | KDM5A (0.51) | KDM5AKDM5BKDM4CKDM4AKEAP1 | |
| SCHEMBL29696445 | 0.84 | BTK (0.52) | — | |
| SCHEMBL19231054 | 0.84 | BTK (0.52) | — | |
| SCHEMBL30697451 | 0.80 | KDM5A (0.45) | KDM5AKDM5B | |
| SCHEMBL23629251 | 0.73 | KDM5A (0.50) | KDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL11660386 | 0.72 | KEAP1 (0.55) | KEAP1 | |
| SCHEMBL2749580 | 0.70 | KDM5A (0.50) | KDM5AKDM5BKDM4CKDM4A | |
| SCHEMBL453513 | 0.70 | KEAP1 (0.49) | KDM5AKDM5BKDM4CKDM4AKEAP1 | |
| SCHEMBL1456822 | 0.70 | NUDT1 (0.60) | KDM5AKDM4CKDM4A | |
| SCHEMBL14074733 | 0.70 | DYRK1A (0.52) | KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195053-B | Amino acid compounds and methods of use | 普利安特治疗公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-115023419-A | Cereblon-bound piperidine-2, 6-diones and methods of use thereof | 凯普托尔治疗学股份有限公司 | 2022-09-06 | — | — | CN | disclosed |
| EP-4003980-A1 | HETEROBICYCLIC AMIDES AS INHIBITORS OF CD38 | Ribon Therapeutics Inc. (US) | 2022-06-01 | — | — | EP | disclosed |