Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1606347 | 0.74 | L3MBTL1 (0.47) | POLBMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL490219 | 0.74 | CA1 (0.52) | POLBMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL48487 | 0.74 | POLB (0.45) | POLBMAPTHTTL3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL29969139 | 0.72 | CA1 (0.50) | POLBMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL9663002 | 0.72 | POLB (0.43) | POLBMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL2778744 | 0.72 | POLB (0.43) | POLBMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL10263029 | 0.72 | POLB (0.43) | POLBMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL8268468 | 0.72 | POLB (0.43) | POLBMAPTHTTL3MBTL1KMT2A | |
| SCHEMBL799178 | 0.72 | L3MBTL1 (0.50) | POLBMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL28205116 | 0.72 | POLB (0.43) | POLBMAPTHTTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2229377-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | Wyeth LLC (US) | 2010-09-22 | — | — | EP | disclosed |
| WO-2009076602-A1 | 5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS | WYETH (US) | 2009-06-18 | — | — | WO | disclosed |