SCHEMBL490219

SCHEMBL490219

CN1CCN(S(N)(=O)=O)CC1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
POLB P06746 1/20 0.45
L3MBTL1 Q9Y468 3/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ATM Q13315 1/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
USP2 O75604 1/20 0.41
TSHR P16473 2/20 0.39
HTT P42858 2/20 0.38
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
MAPT P10636 1/20 0.38
LMNA P02545 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29969139 0.97 CA1 (0.50) CA1CA2POLBL3MBTL1MEN1
SCHEMBL4141702 0.84
SCHEMBL11688163 0.84 CA1 (0.69) CA1CA2POLBL3MBTL1KMT2A
SCHEMBL48487 0.77 POLB (0.45) POLBL3MBTL1MEN1KMT2ANPSR1
SCHEMBL1606347 0.77 L3MBTL1 (0.47) POLBL3MBTL1MEN1KMT2ANPSR1
SCHEMBL2969669 0.74 POLB (0.43) POLBL3MBTL1MEN1KMT2ANPSR1
SCHEMBL1487100 0.74 CA1 (0.50) CA1CA2POLBL3MBTL1NPSR1
SCHEMBL8268468 0.74 POLB (0.43) POLBL3MBTL1MEN1KMT2ANPSR1
SCHEMBL9663002 0.74 POLB (0.43) POLBL3MBTL1MEN1KMT2ANPSR1
SCHEMBL2778744 0.74 POLB (0.43) POLBL3MBTL1MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116754695-B Derivatization detection method for chlorosulfonyl isocyanate 长沙晨辰医药科技有限公司 2023-11-03 CN claimed
WO-2025227032-A1 METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES REMIX THERAPEUTICS INC. (US) 2025-10-30 WO disclosed
US-12187742-B2 Dual ATM and DNA-PK inhibitors for use in anti-tumor therapy XRAD THERAPEUTICS, INC. (US) 2025-01-07 US disclosed
US-12059420-B2 Inhibitors of indoleamine 2,3-dioxygenase and methods of their use BRISTOL-MYERS SQUIBB COMPANY (US) 2024-08-13 US disclosed
EP-3416948-B1 INDACENE BEARING SULFONYLUREAS AS ANTI-INFLAMMATORY AGENTS UNIV QUEENSLAND (AU) 2024-07-24 EP disclosed
CN-115322176-B 2, 3-dihydrobenzofuranyl substituted 1H-indazole compound and preparation and application thereof 温州医科大学 2024-04-16 CN disclosed
US-11858922-B2 Sulfonylureas and related compounds and use of same THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-02 US disclosed
US-11858922-B2 Sulfonylureas and related compounds and use of same THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-02 US disclosed
US-11858922-B2 Sulfonylureas and related compounds and use of same THE UNIVERSITY OF QUEENSLAND (AU) 2024-01-02 US disclosed
CN-116754695-B Derivatization detection method for chlorosulfonyl isocyanate 长沙晨辰医药科技有限公司 2023-11-03 CN disclosed
EP-0873123-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1998-10-28 EP disclosed
WO-1997017070-A1 INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES UNIVERSITY OF PITTSBURGH (US) 1997-05-15 WO disclosed
US-5373000-A Antibacterial agent against both grampositive and gramnegative bacterias EISAI CO., LTD. (JP) 1994-12-13 US disclosed
US-5089491-A Active against both gram-negative and gram-positive bacteria EISAI CO., LTD. (JP) 1992-02-18 US disclosed
EP-0264091-B1 3-PROPENYLCEPHEM DERIVATIVE, PREPARATION THEREOF, CHEMICAL INTERMEDIATES THEREIN, PHARMACEUTICAL COMPOSITION AND USE Eisai Co., Ltd. (JP) 1992-02-05 EP disclosed
US-5066812-A Chemical intermediates for bactericides EISAI CO., LTD. (JP) 1991-11-19 US disclosed
US-5006649-A Bactericides EISAI, CO. (JP) 1991-04-09 US disclosed
US-4921850-A GRAMNEGATIVE AND GRAMPOSITIVE BACTERICIDE EISAI CO., LTD. (JP) 1990-05-01 US disclosed
EP-0329785-A1 CEPHALOSPORIN DERIVATIVES Eisai Co., Ltd. (JP) 1989-08-30 EP disclosed
EP-0264091-A2 3-Propenylcephem derivative, preparation thereof, chemical intermediates therein, pharmaceutical composition and use Eisai Co., Ltd. (JP) 1988-04-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12059420-B2 Inhibitors of indoleamine 2,3-dioxygenase and methods of their use IDO1, IDO2, INMT CA1 806/4885CA2 453/4885POLB 1902/4885
US-11858922-B2 Sulfonylureas and related compounds and use of same NLRP3, NOD1, PYCARD CA1 2921/4885CA2 1151/4885POLB 4795/4885
US-12187742-B2 Dual ATM and DNA-PK inhibitors for use in anti-tumor therapy ATM, CHEK2, CHEK1 CA1 4810/4885CA2 4355/4885POLB 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.