Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.47 |
| ▸ | AR | P10275 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24564645 | 1.00 | MEN1 (0.50) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL29697148 | 0.88 | HRH3 (0.50) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL29696971 | 0.88 | AR (0.52) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL24564593 | 0.88 | AR (0.52) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL24564742 | 0.88 | HRH3 (0.50) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL24564638 | 0.87 | SIGMAR1 (0.54) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL24564541 | 0.86 | MEN1 (0.55) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL24581213 | 0.86 | ALDH1A1 (0.42) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL24564631 | 0.83 | SIGMAR1 (0.54) | MEN1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL24564625 | 0.82 | MEN1 (0.55) | MEN1ALDH1A1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140464-A1 | COMPOUNDS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS BY TARGETING HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |