Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24564714 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPK1LMNAMAPT | |
| SCHEMBL24564698 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPK1LMNAMAPT | |
| SCHEMBL24564689 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPK1LMNAMAPT | |
| SCHEMBL24564690 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPK1LMNAMAPT | |
| SCHEMBL24564561 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPK1LMNAMAPT | |
| SCHEMBL24564644 | 1.00 | ALDH1A1 (0.45) | ALDH1A1ALOX15MAPK1LMNAMAPT | |
| SCHEMBL24581234 | 0.91 | LMNA (0.42) | ALDH1A1LMNAMAPTL3MBTL1HRH3 | |
| SCHEMBL24581205 | 0.91 | LMNA (0.42) | ALDH1A1LMNAMAPTL3MBTL1HRH3 | |
| SCHEMBL23957498 | 0.83 | MAPT (0.48) | ALDH1A1LMNAMAPTL3MBTL1KMT2A | |
| SCHEMBL24564713 | 0.82 | ALDH1A1 (0.47) | ALDH1A1ALOX15MAPK1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140464-A1 | COMPOUNDS AND METHODS FOR TREATING AUTOIMMUNE DISORDERS BY TARGETING HLA-DQ2 | IMMUNOMOLECULAR THERAPEUTICS, INC. (US) | 2022-06-30 | — | — | WO | disclosed |