Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 8/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6011647 | 0.71 | CYP1A2 (0.69) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL4863737 | 0.70 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL8711737 | 0.70 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL4365617 | 0.70 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL13061283 | 0.69 | IDO1 (0.53) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL4365614 | 0.68 | IDO1 (0.50) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL15457410 | 0.68 | IDO1 (0.70) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL11353946 | 0.67 | CYP1A2 (0.69) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL16553471 | 0.67 | PYCR1 (0.61) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| Trimethylammonium SCHEMBL11564446 | 0.67 | IDO1 (0.54) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765474-B1 | CYCLOPENTANE-BASED MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER (US) | 2022-06-15 | — | — | EP | disclosed |