Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 12/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716375 | 0.74 | IDO1 (0.46) | CYP1A2CYP2C19CYP2C9MAPK1IDO1 | |
| SCHEMBL4863737 | 0.73 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL9715921 | 0.73 | IDO1 (0.58) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL29697198 | 0.70 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL6011647 | 0.70 | CYP1A2 (0.69) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL14959149 | 0.70 | IDO1 (0.54) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL11353946 | 0.70 | CYP1A2 (0.69) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL11443342 | 0.69 | IDO1 (0.64) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL11228484 | 0.68 | CYP1A2 (0.80) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 | |
| SCHEMBL10724739 | 0.68 | CYP1A2 (0.71) | CYP1A2CYP3A4CYP2C19CYP2C9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750666-A | FOR SYNTHESIZING NEW MONONUCLEOTIDES AND POLYNUCLEOTIDES HAVING PHOSPHOROTHIOATE AND PHOSPHORODITHIOATE INTERNUCLEOTIDE LINKAGES | COMPETITVE TECHNOLOGIES, INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5684148-A | NUCLEOSIDES AND POLYNUCLEOTIDES AS FLUORESCENT AGENTS FOR MEDICAL DIAGNOSIS | COMPETITIVE TECHNOLOGIES, INC. (US) | 1997-11-04 | — | — | US | disclosed |
| US-5602244-A | DINUCLEOSIDE PRECURSORS IN OLIGONUCLEOTIDE SYNTHESIS; USEFUL AS ANTISENSE INHIBITORS OF TRANSLATION | COMPETITIVE TECHNOLOGIES, INC. (US) | 1997-02-11 | — | — | US | disclosed |
| US-5218103-A | Nucleoside thiophosphoramidites | UNIVERSITY PATENTS, INC. (US) | 1993-06-08 | — | — | US | disclosed |
| WO-1991004983-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1991-04-18 | — | — | WO | disclosed |