Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24589991 | 1.00 | NT5E (0.38) | NT5EL3MBTL1ALDH1A1GABRPGABRD | |
| SCHEMBL13374135 | 0.85 | LMNA (0.39) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL30586208 | 0.84 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL23269411 | 0.84 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL15110967 | 0.83 | HTT (0.40) | NT5EALDH1A1GABRPGABRDGABRA1 | |
| SCHEMBL28287225 | 0.75 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL30402943 | 0.75 | L3MBTL1 (0.40) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL31320068 | 0.74 | KHK (0.42) | NT5EALDH1A1GABRA1GABRG2GABRB3 | |
| SCHEMBL15111309 | 0.74 | KDM4E (0.37) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL15110846 | 0.73 | HTT (0.38) | ALDH1A1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964636-B | Triazolopyrimidines method for synthesizing compound | 上海陶术生物科技股份有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-117964636-A | Synthesis method of triazolopyrimidine compound | 上海陶术生物科技有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117964636-B | Triazolopyrimidines method for synthesizing compound | 上海陶术生物科技股份有限公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-117964636-A | Synthesis method of triazolopyrimidine compound | 上海陶术生物科技有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2022135390-A1 | KETOHEXOKINASE INHIBITOR AND USE THEREOF | 四川海思科制药有限公司 | 2022-06-30 | — | — | WO | disclosed |