Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | BCL6 | P41182 | 3/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22978550 | 1.00 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DDPP4 | |
| SCHEMBL22978633 | 0.86 | BCL6 (0.36) | DPP4BCL6TUBB4ATUBBTUBA3C | |
| SCHEMBL24667673 | 0.85 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DDPP4 | |
| SCHEMBL30918494 | 0.84 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DDPP4 | |
| SCHEMBL3930071 | 0.84 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DDPP4 | |
| SCHEMBL22978520 | 0.84 | S1PR1 (0.40) | PTGS1ALDH1A1HTT | |
| SCHEMBL22978506 | 0.81 | P2RX3 (0.35) | BCL6TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL22978533 | 0.81 | TUBB4A (0.34) | BCL6TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL26180976 | 0.80 | CYP3A4 (0.45) | RAB9APTGESALOX5PTGS1STAT3 | |
| SCHEMBL4148399 | 0.79 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010334-A1 | HETEROCYCLIC WDR5 INHIBITORS AS ANTI-CANCER COMPOUNDS | Novartis AG (CH) | 2022-06-15 | — | — | EP | disclosed |