Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TYR | P14679 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30627998 | 1.00 | CA2 (0.48) | CA2GABRA1GABRB2ALOX5APFEN1 | |
| SCHEMBL10906475 | 0.81 | CA2 (0.56) | CA2GABRA1GABRB2ALOX5APFEN1 | |
| SCHEMBL16815118 | 0.80 | CA2 (0.50) | CA2GABRA1GABRB2ALOX5APFEN1 | |
| SCHEMBL6061735 | 0.79 | CA2 (0.32) | CA2ALDH1A1TSHRTDP1MAPT | |
| SCHEMBL29601537 | 0.77 | CA2 (0.52) | CA2GABRA1GABRB2ALOX5APFEN1 | |
| SCHEMBL9812320 | 0.77 | CA2 (0.31) | CA2ALDH1A1POLBTSHRTDP1 | |
| SCHEMBL967306 | 0.77 | CA2 (0.52) | CA2GABRA1GABRB2ALOX5APFEN1 | |
| SCHEMBL65428 | 0.77 | CA2 (0.52) | CA2GABRA1GABRB2ALOX5APFEN1 | |
| SCHEMBL17363913 | 0.77 | CA2 (0.52) | CA2GABRA1GABRB2ALOX5APFEN1 | |
| SCHEMBL30772983 | 0.77 | CA2 (0.52) | CA2GABRA1GABRB2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105907444-A | Additive containing thiadiazole derivative, nano copper and graphene, preparation method of the additive, and lubricant oil containing the additive | 济宁利特纳米技术有限责任公司 | 2016-08-31 | — | — | CN | claimed |
| CN-105886002-A | Lubricating oil additive containing thiadiazole derivatives and nano copper, preparation method of additive and lubricating oil containing additive | 济宁利特纳米技术有限责任公司 | 2016-08-24 | — | — | CN | claimed |
| EP-3053992-A1 | Biodiesel | LANXESS Deutschland GmbH (DE) | 2016-08-10 | — | — | EP | claimed |
| CN-105061361-A | Nanometer anti-wear particle formed through reaction of thiadiazole derivative and rare earth element, and preparation method and application thereof | YANTAI HENGNUO CHEMICAL TECHNOLOGY CO LTD | 2015-11-18 | — | — | CN | claimed |
| CN-113164941-B | Catalyst system comprising a metathesis catalyst and at least one phenolic compound and method for metathesis of nitrile rubber (NBR) using the catalyst system | 阿朗新科德国有限责任公司 | 2023-12-12 | — | — | CN | disclosed |
| US-11673130-B2 | Catalyst system containing a metathesis catalyst and at least one phenolic compound and a process for metathesis of nitrile-butadiene rubber (NBR) using the catalyst system | ARLANXEO DEUTSCHLAND GMBH (DE) | 2023-06-13 | — | — | US | disclosed |
| US-20220032279-A1 | CATALYST SYSTEM CONTAINING A METATHESIS CATALYST AND AT LEAST ONE PHENOLIC COMPOUND AND A PROCESS FOR METATHESIS OF NITRILE-BUTADIENE RUBBER (NBR) USING THE CATALYST SYSTEM | ARLANXEO DEUTSCHLAND GMBH (DE) | 2022-02-03 | — | — | US | disclosed |
| EP-3894074-A2 | CATALYST SYSTEM CONTAINING A METATHESIS CATALYST AND AT LEAST ONE PHENOLIC COMPOUND AND A PROCESS FOR METATHESIS OF NITRILE-BUTADIENE RUBBER (NBR) USING THE CATALYST SYSTEM | ARLANXEO Deutschland GmbH (DE) | 2021-10-20 | — | — | EP | disclosed |
| CN-113164941-A | Catalyst system comprising a metathesis catalyst and at least one phenolic compound and process for the metathesis of nitrile rubber (NBR) using the catalyst system | 阿朗新科德国有限责任公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020120207-A2 | CATALYST SYSTEM CONTAINING A METATHESIS CATALYST AND AT LEAST ONE PHENOLIC COMPOUND AND A PROCESS FOR METATHESIS OF NITRILE-BUTADIENE RUBBER (NBR) USING THE CATALYST SYSTEM | ARLANXEO DEUTSCHLAND GMBH (DE) | 2020-06-18 | — | — | WO | disclosed |
| EP-3053992-A1 | Biodiesel | LANXESS Deutschland GmbH (DE) | 2016-08-10 | — | — | EP | disclosed |
| CN-105838479-A | Thiadiazole-derivative/graphene-containing lubricating oil additive and preparation method thereof, and lubricating oil containing additive | 济宁利特纳米技术有限责任公司 | 2016-08-10 | — | — | CN | disclosed |
| US-8354427-B2 | Modulators of ATP-binding cassette transporters | VERTEX PHARMACEUTICAL INCORPORATED (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120309758-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-12-06 | — | — | US | disclosed |
| US-20120309758-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-12-06 | — | — | US | disclosed |
| US-20120309758-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-12-06 | — | — | US | disclosed |
| WO-2011072241-A9 | 4-OXO-1H-QUINOLINE-3-CARBOXAMIDES AS MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-06-14 | — | — | WO | disclosed |
| US-20100184739-A1 | Modulators of ATP-Binding Cassette Transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-07-22 | — | — | US | disclosed |
| US-20100184739-A1 | Modulators of ATP-Binding Cassette Transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-07-22 | — | — | US | disclosed |
| US-20100184739-A1 | Modulators of ATP-Binding Cassette Transporters | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184739-A1 | Modulators of ATP-Binding Cassette Transporters | CFTR, ABCB1, ABCC2 | CA2 2330/4885GABRA1 1047/4885GABRB2 336/4885 |
| US-20120309758-A1 | MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS | CFTR, ABCB1, ABCC2 | CA2 2330/4885GABRA1 1047/4885GABRB2 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.