Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4249310 | 0.85 | ALDH1A1 (0.50) | POLBALDH1A1HTTHPGDALOX15 | |
| SCHEMBL28277828 | 0.83 | ALDH1A1 (0.45) | POLBALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL28281091 | 0.82 | AKR1C3 (0.50) | POLBALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL28286413 | 0.81 | MEN1 (0.45) | POLBALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL28286414 | 0.81 | CSNK2A1 (0.49) | POLBALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL11347335 | 0.80 | RXFP1 (0.47) | ALDH1A1MEN1KMT2ARAB9AHTT | |
| SCHEMBL18158039 | 0.79 | ALDH1A1 (0.56) | POLBALDH1A1HTTHPGDALOX15 | |
| SCHEMBL6120416 | 0.79 | TSHR (0.44) | POLBALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL6875951 | 0.77 | ACHE (0.41) | ALDH1A1RAB9ANPC1JAK2HTT | |
| SCHEMBL13367468 | 0.76 | CSF1R (0.45) | HSD17B1HSD17B2MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109516963-B | Method for preparing 1, 2-dihydro- (4H) -3, 1-benzoxazine-4-one compound | 上海交通大学 | 2022-07-01 | — | — | CN | claimed |
| CN-109516963-B | Method for preparing 1, 2-dihydro- (4H) -3, 1-benzoxazine-4-one compound | 上海交通大学 | 2022-07-01 | — | — | CN | disclosed |