Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | TRPV4 | Q9HBA0 | 6/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | TACR3 | P29371 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1719404 | 1.00 | ACACB (0.44) | ACACBACACAL3MBTL3L3MBTL1TRPV4 | |
| SCHEMBL1718933 | 0.89 | GRM5 (0.41) | ACACBACACAL3MBTL3L3MBTL1TRPV4 | |
| SCHEMBL1719218 | 0.87 | CYP2D6 (0.41) | L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL29698740 | 0.87 | CYP2D6 (0.41) | L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL1719382 | 0.86 | IRAK4 (0.45) | ACACBACACAL3MBTL3L3MBTL1TRPV4 | |
| SCHEMBL1718938 | 0.86 | L3MBTL3 (0.44) | ACACBACACAL3MBTL3L3MBTL1TRPV4 | |
| SCHEMBL1719974 | 0.85 | TRPV4 (0.43) | ACACBACACAL3MBTL3L3MBTL1TRPV4 | |
| SCHEMBL1719041 | 0.83 | ACACB (0.43) | ACACBACACAL3MBTL3L3MBTL1TRPV4 | |
| SCHEMBL1720532 | 0.83 | CYP2C9 (0.49) | ACACBACACAL3MBTL3L3MBTL1TRPV4 | |
| SCHEMBL1421309 | 0.82 | ACACB (0.43) | ACACBACACAL3MBTL3L3MBTL1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076602-A | Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses | 嘉兴优博生物技术有限公司 | 2024-05-24 | — | — | CN | disclosed |
| EP-4255903-A1 | HETEROARYL-ACETYLENES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | Eubulus Biotherapeutics Inc. (CN) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022117064-A1 | HETEROARYL-ACETYLENES, PHARMACEUTICAL COMPOSITIONS THEREOF, AND THEIR THERAPEUTIC APPLICATIONS | EUBULUS BIOTHERAPEUTICS INC. (CN) | 2022-06-09 | — | — | WO | disclosed |